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Proposed mechanisms include enhanced long-term potentiation (a cellular correlate of learning), increased brain-derived neurotrophic factor expression, reduced neuroinflammation, and protection against oxidative stress

Although our knowledge of the underlying mechanisms has increased, we need more clinical trials before we can adopt tetracyclines as routine treatment in sepsis and ARDS

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National Institutes of Health to improve disease prevention and formulate personalized treatment by studying genomic, epidemiological and clinical data